Oh, absolutely! A lot of teenagers whose mothers had problems with they call Polycystic Ovarian Syndrome or problem with progesterone deficiency with PMS symptoms. And, I’ve seen a lot of young girls; 12-years old at menarche begin to have anovulatory periods, progesterone dominance, would gain weight, and some of them clearly have what we call polycystic ovarian syndrome.
Others just have a deficiency of progesterone and require progesterone therapy. And, progesterone therapy has absolutely no side effects at all.